Can I get admission in a good college after completing B.com with 43%?

You could look at developing a good profile through your job to help you gain an advantage to offset your disadvantage in scores.

You can, write your qualifying exams very well (i.e. CAT/XAT or another). Marks will affect your interview calls but with a very good qualifying score you can overcome that. Later in the interviews you will have to show your commitment for the program. Any other achievements you have will strengthen