Can I get the short notes of HMP Shunt Pathways?

The Hexose MonoPhosphate Shunt is also known as Pentose Phosphate Pathway (PPP). This is alternative glucose oxidation pathway. The hexose monophosphate pathway is used for production of NADPH from NADP. The NADPH is required for biosynthetic reactions such as fatty acid synthesis, cholesterol synthesis, drug reduction, and as a cofactor for some non-synthetic enzymatic reactions. Hexose Monophospahte shunt is the alternative glucose oxidative pathway. In addition, it is used for the production of ribose for nucleotide and nucleic acid synthesis. The hexose monophosphate shunt is also allows the entry of some carbohydrates into the glycolytic pathway. Therefore, acts as a connection route between different pathways. Glycolysis Glucose Catabolic Pathway Citric acid cycle: Central metabolic cycle and its significance Steroidogenic tissues, red blood cells, and the liver are the major sites of hexose monophosphate pathway. Muscle has small amounts of some of the Hexose MonoPhosphate Shunt enzymes, because it has little need for synthetic reactions, and therefore, little need for NADPH.

0 Upvotes 0 Upvotes 1 Downvote

• • Report Abuse
• Comment