I got 80% marks in 10th standard, now in class 12 science. but not interested in science at all. what should i do after h.s.?

Sandhi, You can pursue Life Science courses in Degree (if you have Bio in your HSC) else you can pursue Law or Commerce/ Management Courses in Degree

Go for fields like Law,Design,Graduation etc which are completely non-science on the basis of your interest. You can work out well in these fields if you work hard.