Is it compulsory to study maths in B.Tech biotechnology at IPU?

No, there is no compulsion for Maths.

Hi, Eligibility Criteria for B.Tech biotechnology at IPU: A Candidate Must have passed 10+2 pattern of CBSE or equivalent with a minimum aggregate of 55% marks in Physics, Chemistry and Mathematics provided the candidate has passed in each subject separately. Candidate must additionally have passed

No, it is not necessary, but the mandatory subjects are Physics, Chemistry and one of the subject from Biotechnology, Biology, Mathematics. https://www.google.co.in/amp/s/www.shiksha.com/b-tech/course/amp/b-tech-in-bio-technology-guru-gobind-singh-indraprastha-university-dwarka-Delhi-108839 For more