My brother dropped 2 years after 12th due to health issues and now completed his B.Com. Will he able to get a good job after completing MBA?

Only MAT and CMAT healthy scores can revive you. As through higher score you will get top tier I branded colleges which can revive you from this dilemma. Chase SIMSREE, PUMBA, XIME (finance and HR too good), Great Lakes-Chennai, N L Dalmia (core finance), IMT-Nagpur and Hyderabad. Do not run behind

Yes, why not. He can surely get a reasonable good job and make a career in the commerce line. I suggest he either do M.Com or MBA with specialization in the field which is related to the job/career he wants for himself or which he can do with ease.