What are enzyme inhibitors? Classify them on the basis of their mode of attachments on the active site of enzymes. With the help of diagrams explain how do inhibitors inhibit the enzymatic activity.

This is a long answer type question as classified in NCERT Exemplar

Enzyme inhibitors block the binding site of enzyme and prevent the binding of substrate and then inhibit the catalytic activity of enzyme. They act in two different ways.

(i) Drugs which compete with substrate for their attachment on the active sites of enzymes are called competitive inhibitor.

(ii) Some drugs bind to a different site of enzyme called allosteric site. It changes the shape of the active site and substrate cannot recognize it. Such enzymes are called non-competitive inhibitor the bond formed between enzyme and an inhibitor is strong covalent bond then enz

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This is a long answer type question as classified in NCERT Exemplar

Enzyme inhibitors block the binding site of enzyme and prevent the binding of substrate and then inhibit the catalytic activity of enzyme. They act in two different ways.

(i) Drugs which compete with substrate for their attachment on the active sites of enzymes are called competitive inhibitor.

(ii) Some drugs bind to a different site of enzyme called allosteric site. It changes the shape of the active site and substrate cannot recognize it. Such enzymes are called non-competitive inhibitor the bond formed between enzyme and an inhibitor is strong covalent bond then enzyme is blocked permanently.

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<p><span data-teams="true">This is a long answer type question as classified in NCERT Exemplar</span></p><p><span data-teams="true">Enzyme inhibitors block the binding site of enzyme and prevent the binding of substrate and then inhibit the catalytic activity of enzyme. They act in two different ways.<br></span></p><p><span data-teams="true"><strong> (i) </strong>Drugs which compete with substrate for their attachment on the active sites of enzymes are called competitive inhibitor.<br></span></p><p><span data-teams="true"><strong> (ii)</strong> Some drugs bind to a different site of enzyme called allosteric site. It changes the shape of the active site and substrate cannot recognize it. Such enzymes are called non-competitive inhibitor the bond formed between enzyme and an inhibitor is strong covalent bond then enzyme is blocked permanently.<br>&lt;!- [if !supportLineBreakNewLine]-&gt;&lt;!- [endif]-&gt;</span></p><div><div><picture><source srcset="" media=" (max-width: 500px)"><img src="https://images.shiksha.com/mediadata/images/1751004253phpG8GquI.jpeg" alt="" width="492" height="185" loading="lazy"></picture></div></div>

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