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The main differences are that B.Tech CSE is a four-year engineering degree with a strong focus on theoretical and practical aspects of both software and hardware, while BCA is a three-year professional degree that focuses primarily on the practical application of computer science, such as software development and coding skills. B.Tech CSE provides a more in-depth, engineering-oriented education, while BCA offers a more application-focused curriculum, which can make it a faster path to industry entry but may lead to fewer advanced technical roles without further study.