14.30 What is the difference between a nucleoside and a nucleotide?

14.30

A nucleoside is formed when l-position of a pyrimidine (cytosine, thymine or uracil) or 9- position of a purine (guanine or adenine) base is attached to C-l of sugar (ribose or deoxyribose) by a linkage. Thus in general, nucleosides may be represented as: Sugar-Base.

Nucleoside = sugar + base

On the other hand, all the three basic components of nucleic acids (i.e., pentose sugar, phosphoric acid and base) are present in a nucleotide.These are obtained by esterification of C5' –OH group of the pentose sugar by phosphoric acid. Thus, in general, a nucleotide is represented as:-

Nucleotide= sugar + base + phosphoric acid

<p><strong>14.30</strong></p><p>A nucleoside is formed when l-position of a pyrimidine (cytosine, thymine or uracil) or 9- position of a purine (guanine or adenine) base is attached to C-l of sugar (ribose or deoxyribose) by a linkage. Thus in general, nucleosides may be represented as: Sugar-Base.</p><p>Nucleoside = sugar + base</p><p><picture><img src="https://images.shiksha.com/mediadata/images/articles/1686817163phpXdAOnk.jpeg" alt="" width="156" height="104"></picture></p><p>On the other hand, all the three basic components of nucleic acids (i.e., pentose sugar, phosphoric acid and base) are present in a nucleotide.These are obtained by esterification of C5' –OH group of the pentose sugar by phosphoric acid. Thus, in general, a nucleotide is represented as:-</p><p>Nucleotide= sugar + base + phosphoric acid</p><div><div><picture><img src="https://images.shiksha.com/mediadata/images/articles/1686817191phpRs728v.jpeg" alt="" width="199" height="132"></picture></div></div>

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