Is negative enthalpy the main condition for a reaction to be spontaneous?

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  • We cannot universally say that negative enthalpy is the cause for spontaneity in chemical reactions. Though it is commonly seen in spontaneous reactions that heat releases or follows the exothermic definition, some spontaneous reactions can also absorb heat. They can be endothermic in nature. With that, we get a positive value for enthalpy change. So the better approach is to look into entropy and Gibbs Energy. These two quantities can define or tell us that a chemical process is spontaneous when the total entropy change is positive and when the Gibbs energy change is negative. 

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