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Yes, as a PCB (Physics, Chemistry, Biology) student, you can definitely do B.Tech in Biotechnology, but you need to choose the right colleges because not all accept PCB students. The good thing is that many private universities now allow PCB students without maths. 

Now coming to your main question, here are some of the best colleges (especially relevant options including LPU):

First, Lovely Professional University is a very good option for PCB students. LPU allows admission without maths and focuses on practical learning, labs, and industry exposure. It is also easier to get admission compared to top government colleges, and placements are decent if you build skills.

Second,  Vellore Institute of Technology is one of the top private universities offering B.Tech Biotechnology. It has strong labs, research exposure, and a better overall reputation. Admission is through VITEEE.

Third,  SRM Institute of Science and Technology is another popular choice. It accepts PCB students and provides good infrastructure and industry exposure. Many biotech students choose SRM for its campus and opportunities.

Fourth,  Manipal Institute of Technology also offers biotechnology with good academic structure and global exposure. It is slightly more expensive but worth considering.

Fifth,  Amity University and Sharda University are also options where PCB students can easily get admission and study biotechnology with decent facilities.

One important thing you should clearly understand is that top colleges like IITs and NITs usually require mathematics, so PCB students cannot get B.Tech there. 

So in simple terms, if you want the best balance, LPU, VIT, and SRM are among the top choices for PCB students. If your priority is easier admission and good exposure, LPU is a safe and practical option. If you want higher competition and brand value, then VIT or Manipal can be better.