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Yes in some institutes and No in some institutes, it's possible to study M.Sc. In Physics after B.Tech in Mechanical Engineering. But only few colleges are giving chance for B.Tech students like Delhi University. Do some research about colleges giving this chance and join accordingly.
You would only be accepted to a few institutions if you wanted to pursue an MSc in physics. Traditional universities will not even accept you for a master's degree in physics. Furthermore, btech mechanical engineering is solely based on basic classical mechanics or lower level classical mechanics, the majority of which is newtonian mechanics.
BSc physics is focused on quantum mechanics, and almost all areas of study in BSc physics use quantum mechanics like there isn't any newtonian mechanics in the universe, so whatever they would be thinking in India about degree equivalence, a BSc physics is way higher than a btech mechanical engineering in terms of theoretical knowledge and depth of physics and mathematics, in fact, a BSc physics is way higher than btech, So, if you get into one of those select few universities, you'll have to work extremely hard or you'll end up in hell. Also, if you want to study physics overseas, a btech is ineligible for an MSc or MS in physics. Only those with a BSc/BS in physics are eligible. As a result, you won't be able to pursue an MSc in another country because their qualifying standards only allow for BSc/BS physics.

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The 10 Most Important Qualities of the Ideal Graduate Research Candidate
Intelligence (including academic ability, intellect, brightness and common sense) was the most common quality associated with the ideal graduate research candidate. "They need to be bright with a good dose of common sense for work in a research laboratory. "
"The best students are those who are bright enough and motivated enough to work independently and submit high quality prose. "
Independence / Confidence
The ability to work and think independently is one of the basic prerequisites for studying a research degree. Qualities associated with independence were confidence, initiative and the ability to take responsibility. "They should be able to work with minimal supervision, but that does not mean that the supervisor is not available for discussions on the research being undertaken. Commitment
Almost half of the supervisors mentioned commitment (to gain knowledge, to complete work or to do well) as the key to successful research degree completion. Other expressions illustrating commitment were perseverance, persistence, determination, dedication, tenacity, resilience and endurance. "The most important qualities a Ph.D. candidate will need are perseverance and commitment, probably more so than raw intelligence. "
"All of the qualities are important for the student to get the most out of their research degree; but if they have a high level of commitment (I REALLY want to do this, and well) then the rest will usually follow". Literacy / numeracy
Literacy, mostly described as good writing and language skills as well as the ability to express and organise ideas, is highly valued by most supervisors. Some supervisors also require their students to have essential statistical and mathematical skills. "I think that writing ability is very important - it wastes a lot of my time (and the student's) if we have to spend a lot of effort and time on correcting drafts. "
time management
curiosity
enthusiasm
ability to think
hard working
motivation.