What is present in the liver by which ammonia converts it into urea?

0 100 Views | Posted 9 years ago

  • 3 Answers

  • M

    Answered by

    MANJU LAKSHMI

    9 years ago
    Ammonia is converted to urea in the liver via urea cycle. this cycle takes place in the mitochondria of the hepatic cells. For further references check Lehninger's Principles of Biochemistry by Nelson and Cox.
  • Shiksha Ask & Answer

    Answered by

    saumya gupta | Guide-Level 11

    9 years ago
    The conversion of ammonia to urea takes place in liver and to some extent in kidney also known as urea cycleIt is a step by step process catalysed by various enzymes at each stepL-ornithinecarbamoyl phosphate
    L-citrulline
    argininosuccinate
    fumarate
    L-arginine
    L-Asp L-aspartate
    CPS-1 carbamoyl phosphate synthetase I
    OTC Ornithine transcarbamoylase
    ASS argininosuccinate synthetase
    ASL argininosuccinate lyase
    ARG1 arginase 1
    To study the details of urea cycle you can refer any book book of biochemistry
  • Shiksha Ask & Answer

    Answered by

    Renuka Rana Community Manager | Guide-Level 12

    9 years ago
    Ammonia is a toxic by-product of protein metabolism and is generally converted to less toxic substances after it is produced then excreted; mammals convert ammonia to urea. Urea is simpler in structure and less harmful for the body. Ammonia is an extremely toxic base and its accumulation in the body would quickly be fatal.
    However, the liver contains a system of carrier molecules and enzymes which quickly converts the ammonia (and carbon dioxide) into urea.

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