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Yes, it is necessary to have knowledge of grad level mathematics if you're going to pursue a degree in biotech. If you're in 12th standard and if it's possible that you can still add a subject in your current curriculum then go for it.
Mathematics is compulsory for admission in government colleges, only private colleges don't have maths as a compulsory. Since you'll be opting for a biotech course (most probably a B.Tech in biotech) then you will require the knowledge of mathematics (grad level).
If you want to improve your maths grade/score then try consulting Math Online Tutor at: https://tutstu.com/tutors/Math/sub/18/COLLEGE
This way you'll be able to prepare for admission exams at your pace and at your own timings.

Hi,
Hi, Minimum Eligibility to Apply: Graduation50%
Additional Details: Candidate must have completed graduation having minimum percentage with the medium of instruction as English. Candidates must have completed a minimum of 15 years of education (on 10+2+3 or 10+2+4 basis). Those not meeting the eligibility criteria of English medium in graduation are required to submit TOEFL/ NELT/ IELTS score by May 31, 2018. A final year appearing student may also apply on provisional basis.
Entrance exam: IBSAT/GMAT/NMAT by GMAC/CAT
Admission Process
Register and Apply: Interested candidates can apply online/ offline with the required information. Registration open for IBSAT 2017 - Apply Online at www.bit.ly/IBSAT2k17
Group Discussion & Personal Interview (GDPI): Shortlisted candidates will be called for group discussion and personal interview based on scores of IBSAT 2017/ GMAT/ CAT/ NMAT by GMAC
Final Selection Candidates are selected based on IBSAT 2017/ GMAT/ CAT/ NMAT by GMAC score/percentile and performance in Group Discussion, Personal Interview, and the past academic performance (performance in X, XII, and graduation).
https://www.shiksha.com/mba/course/master-of-business-administration-icfai-business-school-ibs-hyderabad-donthanapally-110479

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