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Based on your COMEDK rank of 5428 and 121 marks, you have a decent chance of securing admission in several colleges in Bangalore for CSE (Computer Science and Engineering) or IT (Information Technology). While the availability of seats may vary each year and is subject to change, here are some colleges you can consider based on your rank range:
BMS College of Engineering
Ramaiah Institute of Technology (MSRIT)
Dayananda Sagar College of Engineering
Bangalore Institute of Technology
Nitte Meenakshi Institute of Technology
PES University
RV College of Engineering
Sir M Visvesvaraya Institute of Technology (MVIT)
New Horizon College of Engineering
CMR Institute of Technology
Please note that this list is not exhaustive, and there are other colleges in Bangalore that offer CSE and IT programs. It is recommended to visit the official websites of these colleges and check their admission procedures, counseling processes, and availability of seats for the current academic year. Additionally, consider factors such as college reputation, infrastructure, faculty, and placement records while making your decision. Remember to participate in the counseling process and keep track of the specific admission guidelines provided by COMEDK and the respective colleges to secure admission successfully.

As stated by the CBSE:
Candidates who have secured at least 55% marks (without rounding off) in Masters Degree or equivalent examination from universities/institutions recognised by UGC (on the website: https://www.ugc.ac.in/oldpdf/consolidatedlistofalluniversities.Pdf) in humanities (including languages) and social science, computer science and applications, electronic sciencE, etc. (list of subjects of post-graduation attached at page No. 20) are eligible for this test.
The Other Backward Classes (OBC) belonging to non-creamy layer/scheduled caste (SC)/Scheduled Tribe (ST)/ persons with disability (PwD) category candidates who have secured at least 50% marks (without rounding off) in Masters degree or equivalent examination are eligible for this Test.